An Unbiased View of pentobarbital sodium in humans
An Unbiased View of pentobarbital sodium in humans
Blog Article
pentobarbital will lower the level or effect of saxagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will lessen the level or effect of nisoldipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will decrease the level or effect of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Administer barbiturates with caution in patients with hepatic destruction and at lessened doses initially; barbiturates should not be administered to individuals showing the premonitory signs of hepatic coma
pentobarbital raises toxicity of buprenorphine, lengthy-performing injection by pharmacodynamic synergism. Modify Therapy/Watch Carefully. Coadministration of buprenorphine and benzodiazepines or other CNS depressants increases hazard of adverse reactions together with overdose, respiratory melancholy, and death. Cessation of benzodiazepines or other CNS depressants is most popular typically.
pentobarbital will lessen the level or effect of ondansetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. No dosage adjustment for ondansetron is suggested for individuals on these drugs.
pentobarbital will minimize the level or effect of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or effect of flurbiprofen by influencing hepatic enzyme CYP2C9/10 metabolism. Small/Significance Mysterious.
pentobarbital will decrease the extent or effect of dapsone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
Small (one)pentobarbital will lessen the level or effect of paclitaxel protein sure by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.
Watch Intently (one)pentobarbital will decrease the level or effect of gefitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or effect of mifepristone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. CYP3A4 inducers have not been researched, coadministration not advisable by maker
pentobarbital will lower the extent or effect of pazopanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
The sodium salt takes place like a white, marginally bitter powder that's freely soluble more info in water and alcohol but nearly insoluble in benzene and ether.